INNOVATION CENTRAL
Our team is actively involved in research into the treatment of severe nasal deformities to improve patient care and outcomes. See publications below. In 2013, Doctor Faris and Professor Kevin Shakesheff from the University of Nottingham, Doctor Yen Choo, Jing Yang, Joel Segal and Laura Riaz formed a Tissue Engineering group for use in complete nose reconstructions. We are working on creating a nose created with engineered tissue. The idea is to do this with absorbable biomaterial and stem cells, to reduce the number of surgeries needed to rebuild a nose after a nasal amputation (rhinectomy). We initially use CT scans of the patient's face before surgery to create exact 3D images of the patient's original nose.
THE OPERATION
We then produce the cartilage structure of the patient's nose with absorbable biomaterial and place this structure with cartilage cells derived from the patient's own stem cells. The structure allows the cartilage cells to adhere and create a 3D structure that exactly matches that of the patient's original nose. This cartilage/absorbable biomaterial framework can then be placed into the patient to reconstruct his or her entire nasal cartilage structure, to within less than 1 mm. We hope that this technique can reduce the number of operations and time required to reconstruct an entire nose. Furthermore, because we can create an exact replica of the patient's original nose, we hope this can also improve the final cosmetic result.
SELECTED NOSE RECONSTRUCTION PUBLICATIONS FROM OUR GROUP
- ENCYCLOPEDIA OF OTOLARYNGOLOGY, HEAD AND NECK SURGERY
- RHINOLOGY
- JPRAS
- PLASTIC AND RECONSTRUCTIVE SURGERY
Encyclopedia of Otolaryngology, Head and Neck Surgery, Springer 2012
Faris C, Vuyk H.
Chapter on nose reconstruction in the most comprehensive textbook of ENT surgery yet printed.
An overview of practical guidelines for correction of the deviated, asymmetrical nose
Vuyk HD. Rhinology. 2000
A step-by-step surgical approach to correct a deviated nose.
Repair of nasal septum perforation using differently designed, bilateral intranasal flaps, with non-opposing suture lines
André RF, Lohuis PJ, Vuyk HD. Journal of Plastic Reconstructive Aesthetic Surgery 2006
New technique with results to close a large septal perforation.
The “butterfly graft” as a treatment for internal nasal valve incompetence
André RF, Vuyk HD. Plastic Reconstructive Surgery 2008
Experience in reconstructing the middle part of the nose to improve breathing.
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